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[DOI] [PubMed] [Google Scholar] 58.Lincoff AM, Brown-Frandsen K, Colhoun HM, Deanfield J, Emerson SS, Esbjerg S, et al

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Lactobacillus and Bifidobacterium species that are everyday popular probiotic bacteria have mucosal trophic effects including stimulation of epithelial barrier function, inhibition of pathogen adhesion, regulation of existing microbiota and modulation immune system components (Shanahan, 2010

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In some embodiments, the formulations or compositions described herein are liquids and are administered via narrow gauge needles or cannulas (e.g., 22 gauge needle, 25 gauge needle, or cannula), minimizing damage to the tympanic membrane upon administration

PMID: 29683489